精神保健研究所 精神疾患病態研究部。私たちは「脳とこころの科学」の先駆的研究活動を展開しています。

その他:脳神経画像

国際的なImaging geneticsのコンソーシアムであるENIMAに参加して、データを提供して他施設共同研究による成果を上げています。

  1. ENIGMA-Lateralization group. Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex. Brain Imaging and Behaviour (accepted)
  2. Adams H, (203名中略) Hashimoto R,(341名中205番目)(134名中略)Thompson P. Novel genetic loci underlying human intracranial volume identified through genome-wide association. Nature Neuroscience, (in press)
  3. Thompson P, (29名中略)Hashimoto R, (71名中31番目)Wright M, Ye J, for the ENIGMA Consortium. ENIGMA and the individual: Predicting factors that affect the brain in 35 countries worldwide. NeuroImage (in press)
  4. Hibar DP, (236名中略)Hashimoto R, (294名中238番目)(55名中略), Medland S.E. Common genetic variants influence human subcortical brain structures. Nature 9;520(7546):224-9, 2015.4
  5. Toriumi K, Kondo M, Nagai T, Hashimoto R, Ohi K, Song Z, Tanaka J, Mouri A, Koseki T, Yamamori H, Furukawa-Hibi Y, Mamiya T, Fukushima T, Takeda M, Nitta A, Yamada K, Nabeshima T. Deletion of SHATI/NAT8L increases dopamine D1 receptor on the cell surface in the nucleus accumbens, accelerating methamphetamine dependence. Int J Neuropsychopharmacol, 17:443-453, 2014.1
  6. *Hashimoto R, Hirata Y, Asada T, Yamashita F, Nemoto K, Mori T, Moriguchi Y, Kunugi H, Arima K, Ohnishi T. Effect of the BDNF and the ApoE polymorphisms on disease progression in preclinical Alzheimer’s disease. Genes Brain Behav, 8(1), 43-52, 2009.2
  7. *Hashimoto R, Moriguchi Y, Yamashita F, Mori T, Nemoto K, Okada T, Hori H, Noguchi H, Kunugi H, Ohnishi T. Dose Dependent Effect of the Val66Met Polymorphism of the Brain-Derived Neurotrophic Factor Gene on Memory-Related Hippocampal Activity. Neurosci Res, 61(4):360-367, 2008.8
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